Glossary

Antibody also known immunoglobulin, is a protein produced by lymphoid tissue in response to the presence of a foreign substance called an antigen. Anti-Ro/SSA and Anti-La/SSB Antibodies are antibodies found in people with primary Sjogren's syndrome and other autoimmune diseases such as Lupus.

Antinuclear Antibody (ANA) is a blood test used to help evaluate a person for autoimmune disorders that affect many tissues and organs throughout the body.

Typical Sjogren's Syndrome ANA patterns are SSA/Ro and SSB/La.

Anti-SSB/La is far more specific; 

Anti-SSA/Ro is associated with many autoimmune conditions, but are often present in SS. However, Anti-SSA and Anti-SSB tests are frequently not positive in Sjogren's Syndrome.


anti-Ro/SSA and anti-La/SSB antigen-antibody are anti-nuclear autoantibodies that are associated with many autoimmune diseases including Sjogren's Syndrome.

Autoantibodies are antibodies (immune proteins) that mistakenly target and react with a person's own tissues or organs. One or more autoantibodies may be produced by a person's immune system when it fails to distinguish between "self" and "non-self." labtestsonline.org 

Autoantigen is a antigen that stimulates autoantibodies in the organism that produced it.

Blepharitis means inflammation of the eyelids

Bronchiectasis is a common lung disease characterised by chronic infection in small airways that results in some parts of the lung becoming damaged, allowing infected mucus to build up in pockets. Symptoms include a chronic cough with mucus production. Other symptoms include shortness of breathcoughing up blood, and chest pain. 

C4 levels is a simple blood test that measures the amount of complement C4 circulating in the bloodstream. A low level of C4 is associated with autoimmune diseases and collagen vascular diseases.

CNS = central nervous system 

CPGs = clinical practice guildelines

Electromyography (EMG) measures muscle response or electrical activity in response to a nerve's stimulation of the muscle. The test is used to help detect neuromuscular abnormalities.

Lymphadenopathy is a condition affecting the lymph glands resulting in lymph nodes that are abnormal in either size, feel or number.

Lymphoid tissue is the part of the body's immune system important for the immune response and helps protect it from infection and foreign bodies. Lymphoid tissue is present throughout the body and includes the lymph nodes, spleen, tonsils, adenoids, and other structures. MedicineNet

Meibomian glands, also called tarsal glands, are sebaceous glands at the rim of the eyelids.

Monoclonal Gammopathy is a condition in which an abnormal immunoglobin protein (known as a paraprotein) is found in the blood during standard laboratory blood tests.

Neurological = the science of the nerves and the nervous system.


NonTuberculous Mycobacteria (NTM) is a chronic lung disease
that can damage the lungs.

Pathogenesis = the manner of development of a disease.


Paresthesia is an abnormal sensation such as tingling, pricking, numbness or burning of the skin with no physical cause. The most familiar kind of paresthesia is the sensation known as "pins and needles."

PN = peripheral neuropathy a nervous system condition 

caused by damage of the peripheral nerves. Symptoms are  numbness, pain, and weakness,usually in the hands and feet.


pSS = primary Sjögren syndrome


RF = rheumatoid factor.


Raynaud's syndrome, also known as Raynaud's phenomenon, is a medical condition in which spasms of arteries cause episodes of reduced blood flow. Typically the fingers and other parts of the body feel numb.


Salivary glands are called the parotid and submandibular glands and are located on both sides of the neck just below the ears and under the jaw. 

SGE salivary gland enlargement  

Scintigraphy is the salivary gland scan, also called parotid gland 

scintigraphy, is a non-invasive test. It is a nuclear medicine test that 

evaluates the function of the salivary gland. JOHN HOPKINS