NEUROLOGICAL SYMPTOMS in SJOGREN'S SYNDROME (SS) The involvement of the nerves and nervous system.

Did you know that Neurological Symptoms Strike One in Five Primary Sjogren Patients according to a 2016 study


Neurological symptoms seen in SS include:

Neurologic complications: A PRIMER ON THE NEUROLOGICAL COMPLICATIONS OF SJÖGREN’S By Julius Birnbaum, MD Johns Hopkins Neurology-Rheumatology Clinic

The neurological complications of Sjogren’s syndrome are extensive and range from cognitive difficulties to burning toes and feet.                                                                                                                                       The nervous system is divided into two anatomic compartments:

  1. The “Central Nervous System” – or CNS – includes the brain and the spinal cord;
  2. The “Peripheral Nervous System” – or PNS – includes larger and smaller nerves, connecting muscles to the spinal cord.

Sjögren’s syndrome can cause inflammation and damage to both the CNS and PNS.

Prevalence of neurological manifestations in primary Sjogren's syndrome  (PSS) varies widely from 10 to 60%, with pure or predominantly sensory polyneuropathies as the most common neurologic manifestation (e.g. sensory ataxic or small fiber sensory painful neuropathy). 

Mononeuropathy multiplex, polyradiculopathy, symptomatic dysautonomia, cranial neuropathy, myopathy, and central nervous system involvement are less common. PUBMED ARTICLE
Articles on Neurological Symptoms