Neurological Symptoms in Sjogren's Syndrome
Symptoms include:
  • Cognitive dysfunction or brain fog causes problems with verbal recall, basic arithmetic and concentration
  • Cranial neuropathies including trigeminal neuropathy or facial nerve palsy 
  • Dementia
  • Distal paresthesias (numbness and tingling in fingers and toes)
  • Encephalopathy
  • Lower motor neuron disease 
  • Motor and sensory loss
  • Myelopathy
  • Neurogenic bladder
  • Optic neuropathy
  • Progressive-multiple sclerosis-like syndrome
  • Seizures 
  • Vasculitis

Neurologic complications: A PRIMER ON THE NEUROLOGICAL COMPLICATIONS OF SJÖGREN’S By Julius Birnbaum, MD Johns Hopkins Neurology-Rheumatology Clinic

The neurological complications of Sjogren’s syndrome are extensive and range from cognitive difficulties to burning toes and feet.

The nervous system is divided into two anatomic compartments:

  1. The “Central Nervous System” – or CNS – includes the brain and the spinal cord;
  2. The “Peripheral Nervous System” – or PNS – includes larger and smaller nerves, connecting muscles to the spinal cord.

Sjögren’s syndrome can cause inflammation and damage to both the CNS and PNS.

Articles on Neurological Symptoms