Pain and fatigue in Sjogren's Syndrome
Unfortunately these pains can not simply be removed. It is a matter of trying to make them more tolerable.
Anti-inflammatory drugs (e.g. ibuprofen) may be helpful for controlling joint pain and is often combined with hydroxychloroquine (200 mg once daily)
Steroids may be required in severe cases.
FATIGUE IN SJOGREN'S SYNDROME
There is central fatigue associated with weariness - a worn out feeling.
This is difficult to treat and can only be 'coped with' - strategies include a period of rest in the afternoon, no late nights, regular sleep time.
There is peripheral fatigue which can be due to inflammation of the muscles.