Males with Sjogren's
The male-to-female ratio of Sjogren’s syndrome is 1:9. It is hard to find many other statistics about men or boys with Sjogren's. As with most other autoimmune diseases there is a low ratio of men and no definitive answer on why.

I suspect that many men are not getting a diagnosis of Sjogren's as they are not going to the doctor with their symptoms and if they are many doctors are not considering it as a condition to test for. 

Long-term follow-up in primary Sjögren’s syndrome reveals differences in clinical presentation between female and male patients. 2017; 8: 25. Published online 2017 Aug 8. doi:  10.1186/s13293-017-0146-6 PMCID: PMC5549313  PMID: 28789696

Despite men being less prone to develop autoimmune diseases, male sex has been associated with a more severe disease course in several systemic autoimmune diseases. 

In the present study, we aimed to investigate differences in the clinical presentation of primary Sjögren’s syndrome (pSS) between the sexes and establish whether male sex is associated with a more severe form of long-term pSS.

In summary, they found compelling evidence that the clinical presentation of pSS differs between women and men. The sex-specific preference of some clinical manifestations hints at divergent pathophysiological mechanisms between women and men with pSS. 

Consequently, management of the disease will benefit from sex-specific tailored clinical programs to address complications that are common or expected in the respective sex.

Published in Eye Care

Ocular Complications of Primary Sjögren’s Syndrome in Men in American Journal of Ophthalmology June 30, 2015

  • The authors of this retrospective study found in a population of patients with Sjögren's syndrome (SS) seen at a tertiary care clinic that the ratio of women to men was 10:1. In men, the condition was associated with later age at diagnosis, shorter duration of dry eye symptoms, and greater odds of having a vision-threatening condition such as corneal melt. In this and other studies, men were more likely than women to have systemic manifestations such as vasculitis. The tests typically done for the diagnosis of SS include a serological profile; however, men were four times more likely to have negative results with these tests than women.

  • There is a need for early detection of SS in men because of the severity of their disease, and salivary gland biopsy is the most reliable test for early diagnosis.

A.J.'s Story - he was 9 years old when he was diagnosed with Sjogren's. Read his story here.

Quasarhi has Isaac's Syndrome and Sjogren's. In the video below he give his practical, daily tips on coping with dry mouth, dry eyes and dry skin.

Chronic (nonbacterial) prostatitis can be caused by Sjogren's Syndrome. It can also be called chronic pelvic pain syndrome and is the most common type of prostatitis.
Chronic prostatitis is an inflammation of the prostate gland which is located below a man’s bladder. 
Symptoms include ongoing pain and discomfort in urinary or sexual issues such as pain after urination or ejaculation.
There are many treatment options so see your doctor and don't ignore these problems.

Jeff Loya, a restaurateur, was suffering with pancreatitis when doctors determined that he also had Sjogren’s syndrome. Today, Mr. Loya’s disease flares up on occasion, leaving him with terrible back pain and exhaustion. 


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Cardiff City midfielder Stephen McPhail has shed light on his two-year battle with the debilitating condition Sjogren’s Syndrome. The Republic of Ireland midfielder, who joined Cardiff from Barnsley in 2006 was diagnosed with the condition only months after recovering from stage 2 malt lymphoma, a form of Cancer.

Since then he’s faced a daily battle with pain and fatigue that has, at times made him consider how long he can carry on for.

I tried every medication. Every doctor. Everywhere. Nothing was working for me. It was a bit of a low point. At time I felt like going in a saying enough is enough. I can’t really deal with this any more.”


Below is a video from Stephen McPhail and the British Sjogren's Association where he talks about living with Sjogren's disease.

Difference in Clinical Presentation between Female and Male Patients with Primary Sjogren’s Syndrome at Diagnosis and in Long-Term Follow-upArthritis Rheumatol. 2017; 69 (suppl 10)In the present study, we aimed to identify differences in clinical presentation between the sexes at the time of diagnosis and during long-term follow-up of primary Sjögren’s syndrome (pSS), and to establish whether male sex is associated with a more severe form of pSS.

Primary Sjogren's syndrome in men.  2008 Jul-Aug;37(4):300-5. doi: 10.1080/03009740802001426.    To determine whether there were any clinical and biological differences between male and female patients with primary Sjogren's syndrome (pSS) in a large bicentric series of patient.

Primary Sjögren's syndrome in men. . 1995 Sep; 54(9): 748–751. PMCID: PMC100992

OBJECTIVE To describe the clinical expression of primary Sjögren's syndrome (SS) in men, focusing on extraglandular manifestations (EGM) and serological markers of disease. 


Primary Sjögren's syndrome in men Clinical, serologic, and immunogenetic features


Rodolfo Molina,Thomas T. Provost,Frank C. Arnett,Wilma B. Bias,Marc C. Hochberg,Raymond W. Wilson,Elaine L. Alexander


The American Journal of Medicine




January 1986

Abstract from Science Direct

This study represents the first report of the clinical, serologic, and immunogenetic features of a group of 36 men with primary Sjögren's syndrome, which are contrasted with those of a group of 69 women with primary Sjögren's syndrome. The majority of male patients had extraglandular involvement including articular (78 percent), neurologic (39 percent), inflammatory vascular (25 percent), and lymphoproliferative disorders (17 percent). Although men were at the same risk for the development of extraglandular complications, there were significant serologic and immunogenetic differences. In sharp contrast to women with Sjögren's syndrome, men with Sjögren's syndrome were seronegative with respect to the presence of serum rheumatoid factor (p = 0.008) and antibodies to Ro(SS-A) (p = 0.016).